Thursday, 9th December 49th Annual Scientific Meeting of the Australian and New Zealand Society for Immunology 2021

• The retention of donor tissue-resident leucocytes following transplantation is dependent on the level of major and minor histocompatibility - Sarah Dart
• Type I regulatory cells contribute to the resolution of influenza A infection - Caitlin Abbott
• The role of DOT1L in the regulation of humoral immunity - Liam Kealy
• Deciphering mechanisms of TLR-inducible mitochondrial fission and fission-mediated antimicrobial responses in macrophages - Syeda Farhana Afroz
• Cystic fibrosis airway microbes differentially activate a pathological neutrophil subset - Daniel R Laucirica
• CD103 promotes prolonged interactions between regulatory T cells and CD11c expressing cells in the inflamed dermis - Ursula Norman
• Does FcγRIIb on B cells play a role in the early stages of MS? - Stephanie Trend
• Investigating the role of myeloid cell autophagy in acute and chronic inflammation - James Harris
• Gut microbiota targeted dietary supplements as a potential therapy for type 1 diabetes - Emma E Hamilton-Williams
• Exposure to systemic immunosuppressive ultraviolet radiation alters T cell recirculation through sphingosine-1-phosphate - Scott N Byrne
• High-dimensional flow cytometry panel to analyse natural killer cells in SLE - Nicole L Fewings
• Altered BAFF signalling in MS is associated with aberrant B cell homeostasis and proinflammatory activation - Jonatan Leffler
• Expression of CD49f defines subsets of human regulatory T cells with divergent transcriptional landscape and function that correlate with ulcerative colitis disease activity - Ailin Lepletier
• Investigating GAD65-CAR Tregs as a Novel Therapy for Type 1 Diabetes - Jacqueline Scaffidi
• Delineating the role of IFN-I in the development of spontaneous germinal centres and autoantibody production. - Julia I Ellyard
• Local and systemic effects of narrowband UVB irradiation in mice - Rachael A Ireland
• Discovery and functional validation of an autoimmune disease linked super-enhancer that regulates SATB1 - Katherine A Brown
• Nalfurafine reduces neuroinflammation and drives remyelination in the CNS during demyelinating disease - Anne C La Flamme
• The lysine methyltransferase dot1l is required for regulatory t cell development, stability and function - Jessica Runting
• Interferon-gamma regulates IL-2 signalling in antigen-specific CD8+ T-cells - Gaurang Jhala
• Expression of CYP24A1 and other multiple sclerosis risk genes in peripheral blood indicates response to vitamin D in homeostatic and inflammatory conditions   - Samantha P.L Law
• Exploring the utility of MOG antibody epitopes in predicting a relapsing disease course - Ganesha Liyanage
• The identification of genetic and epigenetic changes that contribute to T1D (type 1 diabetes) progression by ATAC-SEQ (Assay of transposase accessible chromatin with high-throughput sequencing - Ying Wong
• Protection against relapses of disease in a mouse model of multiple sclerosis by a parasite-derived 68-mer peptide - Aakanksha Dixit
• Clonal redemption of human autoantibodies in a mouse model - Christopher J Jara
• Despite no evidence of a T1D-specific clonotype, the ‘X-ID peptide’ stimulates human T1D specific CD4⁺ T-cell responses - Pushpak Bhattacharjee
• Reduced abundance and altered phenotype of regulatory T cells in women with recurrent pregnancy loss - Lachlan Moldenhauer
• Investigating the role of interferon signalling in the CD8 T cell transgenic NOD8.3 model of type 1 diabetes - David J De George
• Deamidation of full-length human C-peptide does not increase its immunogenicity in type 1 diabetes - Abby Foster
• Identifying the functional roles of IL-17RA in type 1 diabetes - Sangjong Yu
• Reduced uterine natural killer cell abundance and impaired spiral artery remodeling following intensive exercise performed before and during pregnancy in mice - Evangeline A Lovell
• JAZF1 shapes the metabolic landscape of human T_reg - Kate L Shepherdson
• Strategies to improve therapeutic applications of mesenchymal stem cells - Rand Zaza
• IL-17RC knockout NOD mice are protected from type 1 diabetes in association with alterations in the gut microbiome - Ashley Nowland
• Understanding the mechanisms regulating GILZ a key determinant of immune responses - Megan Cristofaro
• Using AlphaLISA rapid, low-sample volume, no-wash technology to measure biomarkers modulated by immune and cancer cell interactions in 2D and 3D co-culture models - Elisabetta De Luca
• Cross-reactivity of CD4+ gluten-reactive T cell receptors in Celiac Disease. - Laura Ciacchi
• Human CD8 T-stem cell memory subsets phenotypic and functional characterization are defined by expression of CD122 or CXCR3 - Yanran Zhao
• Characterising the role of human Vδ2 T cells in Plasmodium falciparum specific antibody development - Nicholas Dooley
• Chemokines produced by Herpes Simplex Virus infected Langerhans Cells initiate the viral relay through human Dendritic Cells - Jacinta B Smith
• Relationship between interleukin-13 and transferrin receptor-1 responses in the pathogenesis of asthma  - Amber Pillar
• Streptococcal antigens induce autoimmune carditis and neurobehavioral changes – implications for rheumatic heart disease diagnosis and prevention - Rukshan Ahamed Mohamed Rafeek
• HSV-1 infects Langerhans cells and the novel epidermal dendritic cell, Epi-cDC2s, via different entry pathways - Naomi R Truong
• CD4⁺ T cell recognition of pneumolysin, a pore-forming cytolysin derived from Streptococcus pneumoniae presented by a common HLA-DP allotype - Lisa Ciacchi
• Efficacy of COVID-10 Vaccine BNT162b2 in patients with Follicular Lymphoma and Waldenstrom Macroglobulinemia: - Priyanka Hastak
• Characterisation of a glycolipid-peptide vaccine for prevention of malaria - Yu Cheng Chua
• Lipid composition is altered in immune cells and impacts susceptibility to ferroptosis - Pooranee K Morgan
• The class IIa histone deacetylase Hdac7 uses distinct mechanisms to drive TLR-inducible glycolysis and inflammatory responses in macrophages. - Divya Ramnath
• The emerging role of lipid droplets acting as modulators for innate immune signalling  - Jay Laws
• Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire - Anouk von Borstel
• Characterisation of CD4+ T cell subset DNA methylation profiles by long read sequencing - Chloe Goldsmith
• Role of Microenvironment in Pathological Inflammation - Svetlana Shatunova
• Transient deficiency of PKC isozymes in immature cord blood T cells and their development into Th1/Th2 cell bias - Khalida Perveen
• A history of obesity increases the severity of influenza and induces innate immune training - Ellesandra C Noye
• Interleukin-17 contributes to ross river virus-induced arthritis and myositis - Helen Mostafavi
• Vaccination protects mouse sperm quality after Chlamydia muridarum challenge - Emily R Bryan
• Deciphering the mechanisms of action of vaccine adjuvants in human lymph nodes - Vicki V Stylianou
• The role of MLL1 in tailoring humoral immune responses - Yan Zhang
• In silico analysis for the identification of novel Mycobacterium abscessus virulence factors and vaccine antigens   - Kia Ferrell
• The development of an effective vaccine to protect against female genital tract chlamydial infections - Logan K Trim
• A Vδ3+ subset of MR1 reactive γδ T cells recognise the side of the MR1 molecule - Michael T Rice
• Differential gene expression profiles of lung-resident memory CD4⁺ T cells induced by different pulmonary vaccines against Mycobacterium tuberculosis - Ellis Armitage
• In Vitro Suppression of T Cell Proliferation Is a Conserved Function of Primary and Immortalized Human Cancer-Associated Fibroblast - Mohammed Abuwarwar
• Rab6b localises to the Golgi complex in macrophages and promotes TNF release in response to mycobacterial infection - Leslie C Domínguez Cadena
• Tissue-specific contributions of WNT production and signalling to cytokine and chemokine responses during E. coli infection - Rhiannon A Bolton
• Can Neonatal BCG Vaccination Provide Off-Target Protection Against Respiratory Tract Infections In Infants: Results From The MIS BAIR Randomised Controlled Trial - Nicole L Messina
• miR-652 deletion impacts immune response to intracellular bacterial infection - Maxwell Stevens
• Chlamydia Infection of Macrophages: How Infection Alters and Controls Macrophage Function. - Jay Kim
• Interferon inhibits HSV-1 release from axons of sensory neurons - Kevin Danastas
• Mutants strike back: vaccine-induced antibodies against emerging SARS-CoV-2 RBD variants - Ebene R Haycroft
• The atypical chemokine receptor ACKR4 scavenges soluble and immobilised CCL21 to regulate peripheral dendritic cell migration - Cameron R Bastow
• Basis for the biased T cell response towards an immunodominant CD8⁺ T cell epitope from the SARS-CoV-2 spike protein - Jan Petersen
• Helminth peptide therapy reduces Mycobacterium tuberculosis induced inflammation - Giang HB Le
• Comprehensive transcriptional analysis of the CD4+ memory compartments in Tconv and Treg - Holly A Withers
• Durability of B-cell memory to SARS-CoV-2 infection and vaccination - Gemma E. Hartley
• Microenvironmental regulation of glycosyltransferases involved in antibody Fc glycosylation - Jack Polmear
• The GPR183/oxysterol axis controls macrophage infiltration and inflammation in the lung during influenza infection - Stacey Bartlett
• The good, the bad and the ugly: The heterogenous functional IgA response in convalescent COVID-19 individuals - Samantha K Davis
• Children and adults in a household cohort study have robust longitudinal immune responses following SARS-CoV-2 infection or exposure - Melanie Neeland
• Defining the kinetics of progressive pulmonary inflammation during the onset of silica-induced lung disease - Diana H Quan
• Regulation of tissue resident memory T cells by retinoic acid - Grace Rodrigues
• Deconvolution of circulating and resident memory T cell diversity by high-dimensional single-cell protein expression profiling - Maximilien Evrard
• Genistein targets STING-driven antiviral responses - Michael Gantier
• ‘Metabolic upcycling’ – insights into the metabolic underpinning of Haemophilus influenzae persistence in human airways - Ulrike Kappler
• The gut microbiota influences the immune response to PCV13 vaccination via a MyD88 and B-1 cell dependent pathway. - Saoirse C Benson
• The impact of parasite species on T follicular helper cell responses to malaria in humans - Mayimuna Nalubega
• CD8⁺ T cells specific for an immunodominant SARS-CoV- 2 nucleocapsid epitope cross-react with selective seasonal coronaviruses - Emma J Grant
• New insights into the targets and epitopes of immunity to malaria for vaccine development - Gaoqian Feng
• Immunological Impacts of COVID in Convalescent Patients up to 24 Weeks Post Infection. - Christopher M Hope
• Effect of CpG adjuvants on the induction of protective CD8 T cells immunity against liver stage malaria parasites - Ana Maria Valencia-Hernandez
• Studying lymphocyte differentiation in the spleen via spatial transcriptomics - Cameron Williams
• New insights into STAT3 inborn errors of immunity. - Joseph Mackie
• Characterisation of plasma cell survival reveals a long lived subset that dominates the bone marrow compartment over time  - Rosela Webster
• Kinetics of the complement-fixing antibody response to a panel of Plasmodium vivax proteins following naturally acquired symptomatic P. vivax malaria infections - Rhea Longley
• Investigating the transcription factor control of CD11c+ atypical B cell by novel CRISPR-Cas9 system - Xin Gao
• Molecular mechanisms of apoptosis induction during Salmonella Typhimurium infection - Sven Engel

Registered ASI Members will be emailed the link to join the AGM.

 Speaker: John Fraser